The solubility of one substance in another is a measure of the degree of molecular mixing between the two pure substances at thermodynamic equilibrium. The composition of a saturated solution, expressed as a proportion of a designated solute in a designated solvent, represents this thermodynamic limit of solubility. Accurate determination of the aqueous solubility of pharmaceutical materials is important for understanding both quality control and drug delivery issues for pharmaceutical formulations.
The ability to accurately measure the aqueous solubility of a material is affected by the physico-chemical properties of the material e. Control of these factors during solubility measurements is key to obtaining accurate, reliable values for the equilibrium solubility of a material.
Taste and Odor Organoleptic characteristics are indicated in many instances because they may be useful and descriptive properties of substances. However, they are not meant to be applied as tests for identifying materials.
The inclusion of odor or taste among other descriptive properties may aid in identifying the causative agent following accidental exposure to or contact with a substance. This information is provided as a warning or to make an individual aware of sensations that may be encountered. The use of odor or taste as a test for identification or content is strongly discouraged.
Murtagh Collection. About Search. Enable Autosuggest. You have successfully created a MyAccess Profile for alertsuccessName. Home Books Applied Physical Pharmacy, 2e. Previous Chapter. Next Chapter. Sandmann B. Sandmann, Beverly J. Solubility, Dissolution, and Partitioning. Amiji M. Mansoor M. Amiji, et al. Applied Physical Pharmacy 2e. McGraw Hill; Accessed November 12, Solubility, dissolution, and partitioning. McGraw Hill.
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